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- Effects of testosterone on coronary vasomotor regulation in men with coronary heart disease.
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- They proceed to be used by Olympic level athletes, and have even spread to high school level athletes, noncompetitive bodybuilders and leisure athletes (Sullivan et al 1998; Dhar et al 2007).
We report a case of an acute ST-segment elevation myocardial infarction in a patient with traditional cardiac risk elements using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person additionally had polycythemia, doubtless secondary to high-dose testosterone. The patient underwent profitable percutaneous intervention of the proper coronary artery. Physicians and sufferers ought to pay attention to the medical consequences of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
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Erythrocytosis has been reported as a possible impact of testosterone, which can be helpful in patients with anemia. The greatest threat of erythrocytosis happens with injectable types of testosterone compared with transdermal preparations, especially in supraphysiologic doses. An enhance of as much as 44% of the baseline hematocrit has been reported .
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Rhoden EL, Morgentaler A. Risks of testosterone-replacement remedy and suggestions for monitoring. Testosterone replacement in hypogonadal men with angina improves ischaemic threshold and quality of life. Ajayi AAL, Mathur R, Halushka PV. Testosterone enhance human platelet thromboxane A2 receptor density and aggregation responses.